Low Dose Naltrexone: What It Is, How It Works, and Why It Has to Be Compounded
Curious about LDN? Our compounding pharmacists explain what low dose naltrexone is, what it's used for, and how to get it compounded in Tennessee.
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"You've done the homework. Your pharmacy should match it."
If you're exploring low dose naltrexone, chances are you didn't land here by accident. You've been reading studies. Listening to podcasts. Talking to a functional medicine provider, a rheumatologist, or an integrative physician who suggested LDN might be worth considering.
You've done the homework. What you need now is acompounding pharmacy that treats your prescriptionwith the same precision and care you've put into getting this far.
That's what Kizer Pharmacy was built for.
Naltrexone is a medication originally approved by the FDA at 50 mg doses for specific uses in addiction medicine. At much lower doses — typically between 0.5 mg and 4.5 mg — it has become the subject of growing clinical interest for its potential role in supporting patients with chronic inflammation, autoimmune conditions, and certain pain syndromes.
Because low dose naltrexone is not commercially available in these smaller dosages, it must be custom-compounded by a pharmacy equipped to prepare precise, individualized strengths. The difference between a 1.5 mg dose and a 4.5 mg dose is clinically meaningful, and the pharmacy preparing it needs the facility, equipment, and trained pharmacists to deliver exactly what your prescriber ordered.
LDN is rarely a one-and-done prescription. Most patients work with their provider to find their "sweet spot" — the specific dose where they feel the most benefit with the fewest side effects. That often means starting low and titrating up in small increments (sometimes as fine as 0.25 mg or 0.5 mg) over weeks or months. A precision compounding pharmacy is what makes that kind of careful dialing-in possible.
At Kizer Pharmacy, LDN is compounded as prescribed by your healthcare provider — typically as capsules, though liquid and topical formulations may be appropriate for certain patients — and we're set up to support your provider through every dose adjustment along the way.
A standard retail pharmacy can't fill a low dose naltrexone prescription in the dosages most prescribers write for it. The 50 mg tablets commercially available aren't designed to be split, crushed, or reformulated at home — and trying to DIY a precise 2 mg dose from a 50 mg tablet is neither accurate nor safe.
That's why LDN is a compounded medication. It requires a pharmacy with:
The pharmacy filling your LDN prescription isn't a commodity detail. It's part of your treatment plan.
Precision-compounded medications require precision pharmacy. Here's what sets Kizer Pharmacy apart.
Our compounding facility is built to USP-800 standards — the industry benchmark for safe, accurate handling of active pharmaceutical ingredients.
A level of clinical depth most pharmacies can't match, led by Jason Kizer, PharmD — Menopause Society Certified.
Independently verified as a legitimate, licensed pharmacy in full compliance with state and federal requirements.
More than 20 years of compounding experience in Union City, TN — a local pharmacy West Tennessee trusts.
Talk With a Pharmacist
Whether you're filling a new LDN prescription, transferring from another pharmacy, or just exploring whether low dose naltrexone may be something to discuss with your provider — our pharmacy team is here to help. Just a conversation with a pharmacist who takes compounding seriously.
Low dose naltrexone requires precise compounding and a pharmacy team a provider can call with questions. For more than 20 years, prescribers across West Tennessee have partnered with Kizer Pharmacy for LDN — and turned to our pharmacists as a clinical resource as they explore LDN therapy with their patients.
When your provider partners with Kizer Pharmacy for LDN, your prescription is compounded with the precision the therapy demands.
Low dose naltrexone is a compounded medication prepared at doses much lower than the 50 mg tablets commercially available for other uses. Typical LDN doses range from 0.5 mg to 4.5 mg and are prescribed by a licensed healthcare provider. Because these doses aren't commercially available, LDN must be custom-compounded by a pharmacy equipped for precision preparation — which is what we do at Kizer Pharmacy.
LDN has been the subject of growing clinical interest in the management of certain chronic conditions, including autoimmune disorders, chronic inflammation, and some pain syndromes. The decision to prescribe LDN — and for what condition — is made by your healthcare provider based on your individual medical history and clinical picture. Kizer Pharmacy compounds LDN as prescribed; we do not diagnose or recommend its use.
Naltrexone is commercially available in 50 mg tablets for other FDA-approved uses. The much smaller doses used for LDN — typically 0.5 mg to 4.5 mg — aren't available as a commercial product. A compounding pharmacy like Kizer Pharmacy has the facilities, equipment, and trained pharmacists to prepare LDN in precise, individualized dosages as prescribed by your healthcare provider.
LDN requires a prescription from a licensed healthcare provider — typically a primary care physician, functional medicine provider, rheumatologist, or integrative physician. If you're interested in exploring whether LDN may be appropriate for you, start the conversation with your healthcare provider. Once you have a prescription, our pharmacy team can work directly with your prescriber to compound it.
Yes. If you're currently filling LDN at another pharmacy and want to transfer to Kizer Pharmacy, call us at (731) 885-2226 or schedule a consultation and our team will handle the transfer process with your current pharmacy and your prescribing provider. Most prescription transfers can be completed in a single phone call.
The most common formulation is capsules, compounded in the dosage your healthcare provider prescribes. In some cases, a liquid formulation or other preparation may be appropriate — this decision is made between you and your prescriber. Our pharmacy team can discuss the options available and coordinate with your provider as needed.
Because LDN is a compounded medication, it's prepared fresh for each prescription rather than dispensed from stock. Most LDN prescriptions can be compounded and ready for pickup or shipment within 1–3 business days, depending on our current compounding schedule. If you need your prescription more urgently, let our team know when you call and we'll do our best to accommodate.
Kizer Pharmacy is licensed to dispense compounded medications to patients in Tennessee. Prescription compounds cannot be shipped outside of Tennessee. If you're located elsewhere, we recommend working with a compounding pharmacy licensed in your state — and we're happy to answer general questions about what to look for in a compounding pharmacy.
Coverage for compounded medications varies by insurance plan. Some plans cover compounded LDN, others don't, and some cover it partially. Our pharmacy team can help you understand your options and, if needed, discuss self-pay pricing before we compound your prescription — so there are no surprises.
All prescription medications carry potential risks and benefits that should be discussed with your healthcare provider. LDN has been generally well-tolerated in the clinical contexts it has been studied, though individual responses vary. Your prescriber is the right person to evaluate whether LDN is appropriate for you based on your full medical history. Kizer Pharmacy's role is to compound your prescription accurately, safely, and as directed by your provider.
Curious about LDN? Our compounding pharmacists explain what low dose naltrexone is, what it's used for, and how to get it compounded in Tennessee.
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Low dose naltrexone explained by Dr. Jason Kizer, PharmD. Learn what LDN is, why it must be compounded, dosing, side effects, and how to access it in West Tennessee.
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A compounding pharmacy is a type of pharmacy that can make customized medications to meet specific needs. Licensed pharmacists can make drugs in the strength, dosage, or form that you need to get the most benefits from your medications.
Read articleAll compounded medications are prepared pursuant to a prescription from a licensed healthcare provider. Compounded medications are not FDA-approved and are customized for individual patient needs. Results may vary. Consult your healthcare provider before beginning any new medication or supplement regimen. Kizer Pharmacy and Kizer Wellness is a licensed compounding pharmacy operating under Tennessee Board of Pharmacy regulations and FDA 503A guidelines.